
Product Details
 
 Loxonin S Plus is an antipyretic analgesic that contains both fast-acting ingredients and stomach-friendly ingredients.
 ● Contains an analgesic ingredient (loxoprofen sodium hydrate) that quickly relieves pain.
 ● Combined with ingredients that protect the stomach (magnesium oxide).
 ● Effective one tablet at a time.
 ● Does not contain sleepy ingredients (sedative-hypnotic ingredients).
 ● A small tablet is to easy flip.
 
 
 Ingredients / Amount / Usage
 
 Ingredients / Amount
 This product is a very light red film-coated tablet. Each tablet contains the following ingredients.
 Loxoprofen sodium hydrate ... 68.1mg (60mg as anhydrous)
 Magnesium oxide ... 33.3mg
 Additives: lactose, cellulose, hydroxypropyl cellulose, croscarmellose Na, calcium stearate, hypromellose, titanium oxide, iron sesquioxide, carnauba wax
 
 
 Usage and Dose
 < Usage and Dose >
 Adults (15 years and above): 1 tablet at a time, up to 2 doses per day. When symptoms appear, take it water or lukewarm by avoiding empty stomach. However, if symptoms reappear, you can take a third dose. Please keep 4 hours or more gap between doses.
 Under 15 years old ... Please do not take.
 < Precautions regarding usage and dose >
 (1) Strictly adhere to usage and dose.
 (2) How to take out tablets
 As shown in the figure on the right, press the convex part of the PTP sheet containing the tablet with your fingertips, break the aluminium foil on the back, take it out, and have it. (If accidentally swallowed as it is, it may lead to an unexpected accident such as piercing the mucous membrane of the oesophagus)

 Dosage form/shape
 Film-coated tablets
 
 Efficacy
 
 Indications / Effects
 ○ Headache, menstrual pain (menstrual pain), toothache, pain after extraction, sore throat, low back pain, joint pain, neuralgia, muscle pain, stiff shoulder pain, ear pain, bruise pain, fracture pain, sprain pain, trauma pain relief
 ○ Antipyretic during chills and fever
 
 Precautions 

 Precautions for use
 1． Following persons please do not take it.
 (1) A person who has had an allergic symptom by this agent or ingredient of this agent.
 (2) A person who has had asthma after taking this drug or other antipyretic analgesics or cold medicine.
 (3) Children under 15 years old
 (4) A person who is receiving any of the following treatments in a medical institution.
 Stomach / duodenal ulcer, liver disease, kidney disease, heart disease
 (5) Persons who have been pointed out by a doctor for having blood abnormalities (blood diseases) such as low red blood cell count (anaemia), low platelet count (hard blood does not stop, easy to get blood), low white blood cell count, etc.
 (6) Pregnant women within 12 weeks of the expected date of delivery.
 2．Please do not take any of the following drugs while taking this medicine.
 Other antipyretic analgesics, cold medicines, sedatives
 3．Please do not drink alcohol before and after taking this medicine.
 4.  Please do not it take for a long time.
 (If pain and other symptoms continue after taking 3 to 5 days, stop taking and see a doctor.)
 
 
 Consultation points for use
 1． Following persons should consult a doctor, dentist or pharmacist before the usage.
 (1) A person who is receiving treatments from a doctor or dentist.
 (2) Pregnant woman or person who seems to be pregnant.
 (3) Breastfeeding person.
 (4) Elderly persons.
 (5) A person who has had an allergic reaction caused by a medicine.
 (6) A person who received a diagnosis for followings,
 Bronchial asthma, ulcerative colitis, Crohn's disease, systemic lupus erythematosus, mixed connective tissue disease
 (7) A person who has suffered from the following diseases,
 Stomach / duodenal ulcer, liver disease, kidney disease, blood disease
 
 2． If you have the following symptoms after taking this medicine they may be possible side effects, therefore, immediately stop the usage and consult a doctor,  or a pharmacist with this document.
 (1) After taking antipyretic analgesics such as this drug, symptoms such as excessive body temperature decrease, collapse (no power), limb cooling (cold limbs)
 (2) When peptic ulcer or swelling appears after taking
In rare cases, gastrointestinal bleeding (bleeding, nausea/vomiting, abdominal pain, black tar-like stools, bloody stools, etc.), gastrointestinal perforation (having a hole in the digestive tract, nausea/vomiting, severe abdominal pain, etc.) Serious symptoms such as stenosis/occlusion of the small intestine / large intestine (nausea/vomiting, abdominal pain, bloating, etc. may occur) may occur. In that case, please see a doctor immediately.
(3) If the following symptoms appear after taking
Part concerned: Symptom
Skin: Rash, redness, itch
Digestive: Abdominal pain, stomach discomfort, loss of appetite, nausea/vomiting, bloating, heartburn, stomatitis, indigestion
Cardiovascular: elevated blood pressure, palpitation
CNS: drowsiness, numbness, dizziness, headache
Others: Chest pain, malaise, hot flashes on the face, fever, anaemia, hematuria
In rare cases, the following serious symptoms may occur. In that case, please see a doctor immediately.
Symptom name: Symptom
shock
(Anaphylaxis): Immediately after administration, itching of the skin, hives, vomiting of the voice, sneezing, itchiness of the throat, dyspnea, palpitation, the opacity of consciousness, etc. appear.
Blood disorders: sore throat, fever, general fatigue, whitening of the face and eyelids, easy bleeding (bleeding gums, nosebleeds, etc.), bruising (colour does not disappear when pressed), etc. ..
Mucocutaneous ocular syndrome
(Stevens-Johnson syndrome),
Toxic epidermal necrolysis: High fever, redness of eyes, sore eyes, sore lips, sore throat, widespread rash/redness of the skin, etc. persists or aggravates rapidly.
Renal disorder: fever, rash, decreased urine output, general swelling, general swelling, arthralgia (pain in nodes), diarrhoea, etc. may occur.
Congestive heart failure: General malaise, palpitation, shortness of breath, chest discomfort, chest pain, dizziness, fainting, etc. may occur.
Interstitial pneumonia: Shortness of breath, shortness of breath, emptiness, fever, etc. are seen when climbing stairs or doing too little effort, and these may suddenly appear or persist.
Liver dysfunction: Fever, itch, rash, jaundice (yellowing of the skin and white of the eyes), brown urine, general malaise, loss of appetite, etc. may occur.
Rhabdomyolysis: Pain in the muscles of the limbs, shoulders, lower back, etc., numbness in the limbs, weakness, stiffness, whole body, reddish-brown urine, etc. appear.
Aseptic meningitis: Severe headache with the nape of the neck, fever, nausea/vomiting, etc. may occur. (Such symptoms are most often reported in people who are being treated for systemic lupus erythematosus or mixed connective tissue disease)
Asthma: When you breathe, you may see, squeal and suffocate.

 3． The following symptoms may occur after taking this medicine. If such symptoms persist or increase, discontinue the usage and consult a doctor or pharmacist with this document.
 Mouth dryness, constipation, diarrhoea
 
 4. If symptoms do not improve after taking 1 - 2 times (possibly with other diseases), discontinue the usage and consult a doctor, dentist or pharmacist with this document.
 
 
 Precautions on storage and handling
 (1) Store in a cool place with little moisture and no direct sunlight.
 (2) Please keep out of reach of children.
 (3) Do not replace with other containers. (This may cause misuse or change the quality.)
 (4) Do not use the products that have passed the expiration date.
 
 
 
 Details
 
 
 Product Inquiries
 Daiichi Sankyo Healthcare Co., Ltd. 
 
 103-8234 3-14-10 Nihonbashi, Chuo-ku, Tokyo
 
 Customer Service Office
 0120-337-336
 
 Product size
 45mm in height X 105mm in width X 22mm in depth

