
Product Details

A general cold remedy that contains, 8 types of ingredients that have excellent effects on severe cold symptoms such as sore throat and fever.
1. Two anti-inflammatory components, tranexamic acid and ibuprofen, suppress inflammation that causes painful cold symptoms and exerts excellent effects on sore throat and fever.
2. Cremastine fumarate, a persistent antihistamine component, suppresses allergic symptoms (snot and stuffy nose) of colds.
3. Bromhexine hydrochloride, expectorant components, makes it easier to release the sputum that causes coughing.
4. Dihydrocodeine phosphate and dl-methylephedrine hydrochloride relieve the painful pain.
5. Aluminum PTP packaging that is convenient to carry.


Ingredients, quantity, usage


Ingredient/quantity
This drug is a white film-coated tablet and contains the following ingredients in 6 tablets.
Tranexamic acid...750 mg
(Suppresses [plasmin] under inflammation and suppresses throat swelling and pain.)
Ibuprofen...450 mg
(It works on [prostaglandins] due to inflammation and pain, suppresses sore throat, and lowers fever.)
Cremastine fumarate: 1.34 mg (1 mg as clemastine)
(Allergic symptoms (snot, sneezing, etc.) are suppressed continuously.)
Bromhexine hydrochloride...12 mg
(It makes it easier to put out the sputum, which is one of the causes of coughing.)
dl-methylephedrine hydrochloride...60 mg
(Open the bronchi and reduce the cough.)
Dihydrocodeine phosphate: 24 mg
(Acts at the cough centre and reduces the cough.)
Thiamine Nitride (Vitamin B1 Nitrate)...25 mg
(Promotes recovery of physical strength exhausted by colds.)
Riboflavin (vitamin B2)...12mg
(Keeps mucous membranes such as throat and nose healthy.)
Additives: trehalose, cellulose, macrogol, croscarmellose Na, polyvinyl alcohol (partially saponified product), silicic acid anhydride, hardened oil, Mg stearate, hypromellose, titanium oxide, carnauba wax
[Cautions regarding ingredients and quantity]
Riboflavin (vitamin B2) contained in this drug may cause urine to turn yellow.


Usage and dose
Take the following amount with water or hot water.
Adults (15 years old or above)・・・Take 2 tablets, take 3 times per day, take within 30 minutes after a meal.
Under 15 years old...Please do not take it.
[Precautions regarding usage and dose]
(1) Please adhere strictly to the usage and dose.
(2) How to take out tablets:
Please push the convex part of the PTP sheet containing the tablet strongly with your fingertips to break the aluminium foil on the backside, take it out and have it. (If accidentally swallowed, it may lead to unexpected accidents such as sticking to the mucous membrane of the oesophagus.)


Dosage form/shape
 Film-coated tablets


efficacy

Efficacy
 Alleviation of cold symptoms (throat sore, fever, chills, headache, runny nose, stuffy nose, sneezing, cough, sputum, joint pain, muscle pain)


Precautions

Precautions for use
 (If not followed, the current symptoms will worsen and side effects/accidents will be likely to occur.)
1. Following persons, please do not use the medicine.
(1) People who have had allergic reactions due to this drug or due to its ingredients
(2) People who have had asthma after taking this drug or other cold remedies or antipyretic analgesics.
(3) Children under 15 years old
(4) Pregnant women who are expecting delivery within 12 weeks
2. Do not use any of the following medicines while taking this drug.
Other cold medicines, antipyretic analgesics, sedatives, antitussive expectorants, internal medicines, contained antihistamines (oral medicines for rhinitis, motion sickness medicines, allergy medicines, etc.), oral medicines containing tranexamic acid
3. After taking the drug, please do not operate vehicles or machinery.
(Drowsiness may appear)
4. When breastfeeding, do not take this drug or avoid breast-feeding if taking this drug.
5. Do not drink alcohol before and after having the medicine.
6. Please do not use for more than 5 days.

Consultation points for use
 1. The following people, please consult a doctor, pharmacist or registered seller before the usage.
(1) A person who is receiving treatments from a doctor or a dentist.
(2) Pregnant woman or person who seems to be pregnant
(3) Elderly people
(4) People who have had allergic reactions due to drugs
(5) People with the following symptoms
High fever, difficulty urinating
(6) A person who received a diagnosis for followings,
Thyroid dysfunction, diabetes, heart disease, hypertension, liver disease, kidney disease, glaucoma, systemic lupus erythematosus, mixed connective tissue disease, people with thrombosis (cerebral thrombosis, myocardial infarction, thrombophlebitis, etc.), thrombosis People at risk, respiratory dysfunction, obstructive sleep apnea, obesity
(7) A person who has the following illness.
Gastric/duodenal ulcer, ulcerative colitis, Crohn's disease
2. If the following symptoms appear after the usage, there is a possibility of occurring side effects, in that case, immediately stop the use and consult a doctor, pharmacist or registered seller with this document.
Related parts...Symptoms
Skin: rash/redness, itch, bruise
Digestive system: nausea/vomiting, loss of appetite, stomach discomfort, stomach pain, stomatitis, heartburn, stomach upset, gastrointestinal bleeding, abdominal pain, diarrhoea, bloody stool.
Psychiatric system... dizziness, excitement, cramps
Cardiovascular palpitations
Respiratory...shortness of breath
Urology: Difficult to urinate
Others: Blurred eyes, ears, swelling, nosebleeds, gum bleeding, bleeding is difficult to stop, bleeding, back pain, excessive hypothermia, bloating
In rare cases, the following serious symptoms may occur. In that case, please consult a doctor immediately.
Name of symptom...Symptom
Shock (anaphylaxis): After immediate usage, itching of the skin, hives, tingling of the voice, sneezing, itchiness of the throat, dyspnea, palpitation, an opacity of consciousness, etc. appear.
Mucocutaneous ocular syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis...high fever, redness of eyes, sore eyes, sore lips, widespread skin rash/redness, etc.worsen suddenly.
Liver dysfunction: fever, itch, rash, jaundice (yellowing of the skin and white of the eyes), brown urine, general malaise, loss of appetite, etc.
Renal disorders: fever, rash, decreased urine output, swelling of the whole body, general swelling, joint pain (pain in the nose), diarrhoea, etc.
Aseptic meningitis: Severe headache, fever, nausea/vomiting, etc. accompanied by tightness in the neck. (Such symptoms are often reported among people who are getting treatments for systemic lupus erythematosus or mixed connective tissue disease)
Interstitial pneumonia: Shortness of breath, shortness of breath, emptiness, fever, etc. are seen when climbing stairs or by putting little effort, and these appear suddenly or persist.
Asthma... When you breathe, you will see sighing, humming, and breathlessness.
Aplastic anaemia: bruise, nosebleeds, bleeding gums, fever, pale skin and mucous membranes, fatigue, palpitations, shortness of breath, sickness, hematuria, etc.
Agranulocytosis... Sudden high fever, nausea, sore throat, etc.
Respiratory depression: Shortness of breath, suffocation, etc. may occur.
3. The following symptoms may occur after the usage if such symptoms persist or increase, discontinue the use and consult a doctor, pharmacist or registered seller with this document. Please.
Constipation, mouth dryness, drowsiness
4. If symptoms do not improve after taking for about 5 to 6 times, discontinue the use and consult a doctor, pharmacist or registered seller with this document.
(Especially when the heat continues for more than 3 days, and it repeats)


Precautions for storage and handling
(1) Please store it in a cool, dry place out of direct sunlight.
(2) Please keep out of reach of children.
(3) Do not replace it with another container. (It may cause misuse or quality changes)
(4) Do not use the products that have passed the expiration date on the label.



The details

Product inquiries
 Daiichi Sankyo Healthcare Co., Ltd.  Customer Service Office
103-8234 3-14-10 Nihonbashi, Chuo-ku, Tokyo
0120-337-336

Product size
 Height 75 mm x width 115 mm x depth 28 mm

