
Product Details

This drug is a general cold remedy containing 600 mg (daily dose) of antipyretic and analgesic ingredient "Ibuprofen", which is effective against sore throat colds and hard colds.
When this drug is swallowed, 7 active ingredients that exhibit excellent effects such as anti-inflammatory ingredient "tranexamic acid" and expectorant ingredient "ambroxol hydrochloride" work effectively,
Symptoms of a difficult cold are alleviated and become easier.


Ingredients, quantity, usage

Ingredient/quantity
 [Main component]
(Out of 9 tablets)
Ibuprofen 600 mg
Tranexamic acid 750 mg
Ambroxol hydrochloride 45 mg
d-Chlorpheniramine maleate 3.5 mg
Dihydrocodeine phosphate 24 mg
dl-methylephedrine hydrochloride 60 mg
Anhydrous caffeine 75 mg

【Additive】
Anhydrous silicic acid, hypromellose, citric acid, lactose, Ca silicate, hydroxypropyl cellulose, carmellose Ca, Mg stearate, triacetin, talc, titanium oxide, yellow No. 5, carnauba wax


Usage and dose
 Take the following amount with water or warm water within 30 minutes after eating.
[Age: 1 dose: 1 dose per day]
Adult (15 years old or older): 3 tablets: 3 times
Children under 15 years: Do not take


Dosage form/shape
 tablet


efficacy

Efficacy
 Alleviation of cold symptoms (throat sore, fever, runny nose, stuffy nose, sneezing, cough, sputum, chills, headache, joint pain, muscle pain)


Precautions


Precautions for use
 1. Do not take the following people
(1) People who have had allergic symptoms due to this drug or the ingredients of this drug.
(2) Those who have had asthma after taking this drug or other cold remedies or antipyretic analgesics.
(3) Children under 15 years old.
(4) A person who is receiving medical treatment for the following illness or administration of pharmaceuticals at a medical institution.
Persons taking stomach/duodenal ulcer, blood disease, liver disease, kidney disease, heart disease, hypertension, zidovudine (retrovir)
(5) Pregnant women who are expected to give birth within 12 weeks.
2. Do not use any of the following medications while taking this drug
Oral medicines containing other cold remedies, antipyretic analgesics, sedatives, antitussive expectorants, antihistamines (oral medications for rhinitis, motion sickness medications, allergy medications, etc.), oral medications containing tranexamic acid 
3. Do not drive or operate vehicles after taking
(Drowsiness etc. may occur.)
4. People who are breast-feeding should not take this drug or avoid breast-feeding when taking this drug.
5. Do not drink before and after taking
Do not take more than 6.5 days


Consultation points for use
 1. The following people, please consult your doctor, pharmacist or registered seller before taking
(1) Person who is receiving medical treatment from a doctor or dentist.
(2) Pregnant woman or person who seems to be pregnant.
(3) Elderly people.
(4) People who have had allergic reactions due to drugs etc.
(5) People with the following symptoms. High fever, difficulty urinating
(6) Person who received the next diagnosis.
Thyroid dysfunction, diabetes, glaucoma, systemic lupus erythematosus, mixed connective tissue disease, people with thrombosis (cerebral thrombosis, myocardial infarction, thrombophlebitis), people who may develop thrombosis, bronchial asthma, respiratory dysfunction, Obstructive sleep apnea, obesity
(7) A person who has had the following illness.
Gastric/duodenal ulcer, ulcerative colitis, Crohn's disease, blood disease, liver disease, kidney disease

2. If you experience any of the following symptoms after taking the drug, it may have side effects.Discontinue use immediately and consult your doctor, pharmacist, or registered seller with this package insert.
[Parts involved: symptoms]
Skin: Rash/redness, itch
Digestive system: nausea/vomiting, poor appetite, stomach discomfort, stomach pain, stomatitis, heartburn, stomach upset, gastrointestinal bleeding, abdominal pain, diarrhea, stomach/abdominal bloating
Psychiatry: dizziness, insomnia, mood
Cardiovascular: Palpitations
Respiratory: shortness of breath
Urology: difficulty urinating
Other: Blurred eyes, ears, swelling, back pain, numbness
● In rare cases, the following serious symptoms may occur. In that case, please see a doctor immediately.
[Name of symptom: Symptom]
Shock (anaphylaxis): Immediately after administration, itching of the skin, hives, tingling of the voice, sneezing, itchiness of the throat, dyspnea, palpitation, opacity of consciousness, etc. may occur.
Mucocutaneous ocular syndrome (Stevens-Johnson syndrome): High fever, redness of the eyes, sore eyes, sore lips, sore throat, and widespread rash/redness of the skin persist or rapidly deteriorate.
Toxic epidermal necrolysis: high fever, redness of the eyes, sore eyes, sore lips, sore throat, widespread rash/redness of the skin, etc. persists or deteriorates rapidly.
Liver dysfunction: Fever, itch, rash, jaundice (yellowing of skin and white of eyes), brown urine, general malaise, loss of appetite, etc. may occur.
Renal disorder: Fever, rash, decreased urine output, swelling of the whole body, general swelling, arthralgia (pain in the nodes), diarrhea, etc. may occur.
Aseptic meningitis: Severe headache with nape of the neck, fever, nausea/vomiting, etc. (Such symptoms are especially common in people who are being treated for systemic lupus erythematosus or mixed connective tissue disease.


Precautions for storage and handling
 (1) Avoid high temperatures and store in a cool, dry place protected from direct sunlight.
(2) Please keep out of reach of children.
(3) Do not replace it with another container. (It may cause misuse or the quality may change.)
(4) Be careful to store and carry the PTP so that the aluminum foil is not broken and the capsule inside is not deformed.
(5) Do not take the product after the expiration date (listed on the outer box).


The details

Product inquiries
 Kowa Co., Ltd.  Pharmaceutical Business Department Customer Service Center
3-4-14 Nihonbashihonmachi, Chuo-ku, Tokyo 103-8433
03-3279-7755
Telephone reception hours: Monday to Friday (excluding holidays) 9:00 to 17:00


Product size
 Height 75 mm x width 110 mm x depth 23 mm


